Real Estate Investment Properties for Sale in Seneca, SC

Looking for investment property in Seneca, SC with high ROI ?

Explore a variety of short-term homes & houses in Seneca, SC. Invest wisely with VRBO & Seneca, SC Airbnb properties available for purchase. Find your ideal investment property among our curated listings for a rewarding real estate venture.

Investment Property for Sale in Seneca, SC

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PROPERTY	DETAILS	SALE PRICE	INVESTMENT PERFORMANCE
4014 Creekside Drive Seneca, SC LOCATION! LOCATION! LOCATION! You will love this beautiful ranch style home that is perfe...	3 beds \| 2 baths \| N/A	$245,000	Airbnb cash on cash: 6.72% Traditional cash on cash: 6.22% Airbnb Rental Income: $2550 Traditional Rental Income: $1821 Airbnb ROI: 6.72% Traditional ROI: 6.22%
811 Harts Cove Way Seneca, SC Great opportunity to own a 3 bed 3 bath first floor unit. Walk from your car into your uni...	3 beds \| 3 baths \| N/A	$250,000	Airbnb cash on cash: 5.29% Traditional cash on cash: 6.48% Airbnb Rental Income: $2550 Traditional Rental Income: $2217 Airbnb ROI: 5.29% Traditional ROI: 6.48%
2600 Dog Leg Lane Seneca, SC Welcome Home to Cross Creek, A Gated Golf Community Located In Seneca, SC. Cross Creek Is ...	3 beds \| 3 baths \| N/A	$719,000	Airbnb cash on cash: 1.01% Traditional cash on cash: 1.09% Airbnb Rental Income: $2550 Traditional Rental Income: $1990 Airbnb ROI: 1.01% Traditional ROI: 1.09%
816 Ploma Drive Seneca, SC This Gorgeous home was completely redone in 2021 and still shows like New - Roof, HVAC, ...	3 beds \| 3 baths \| N/A	$475,000	Airbnb cash on cash: 2.67% Traditional cash on cash: 3.43% Airbnb Rental Income: $2550 Traditional Rental Income: $2271 Airbnb ROI: 2.67% Traditional ROI: 3.43%
413 Arbor Way Seneca, SC This 3 bedroom 2 bathroom home is nestled in an interior Lake Keowee neighborhood. Just a ...	3 beds \| 2 baths \| N/A	$440,000	Airbnb cash on cash: 2.92% Traditional cash on cash: 1.99% Airbnb Rental Income: $2550 Traditional Rental Income: $1556 Airbnb ROI: 2.92% Traditional ROI: 1.99%
636 Barnes Road Seneca, SC This well maintained home has a wonderful location, nestled between and amongst Lake Keowe...	3 beds \| 2 baths \| N/A	$349,500	Airbnb cash on cash: 4.05% Traditional cash on cash: 3.84% Airbnb Rental Income: $2550 Traditional Rental Income: $1868 Airbnb ROI: 4.05% Traditional ROI: 3.84%
1513 Harts Ridge Drive Seneca, SC Ready and waiting! Move in ready 3 bed 3 bath parking lot level condominium located minute...	3 beds \| 3 baths \| N/A	$255,000	Airbnb cash on cash: 5.23% Traditional cash on cash: 6.61% Airbnb Rental Income: $2550 Traditional Rental Income: $2269 Airbnb ROI: 5.23% Traditional ROI: 6.61%
701 Bogey Boulevard Seneca, SC Welcome to beautiful Cross Creek where you'll experience the best of golf course living. M...	4 beds \| 4 baths \| N/A	$459,900	Airbnb cash on cash: 7.33% Traditional cash on cash: 5.72% Airbnb Rental Income: $5011 Traditional Rental Income: $3294 Airbnb ROI: 7.33% Traditional ROI: 5.72%
215 Elderberry Way Seneca, SC Welcome to 215 Elderberry Way, nestled in nature on the shores of Lake Keowee. For anyone...	4 beds \| 4 baths \| N/A	$1,460,000	Airbnb cash on cash: 1.75% Traditional cash on cash: 1.76% Airbnb Rental Income: $5011 Traditional Rental Income: $4001 Airbnb ROI: 1.75% Traditional ROI: 1.76%
511 Queen Annes Lane Seneca, SC No showings until January 5. Just outside the city limits, this Lake Keowee waterfront hom...	4 beds \| 3 baths \| N/A	$1,300,000	Airbnb cash on cash: 2.06% Traditional cash on cash: 0.99% Airbnb Rental Income: $5011 Traditional Rental Income: $2697 Airbnb ROI: 2.06% Traditional ROI: 0.99%
122 Fair Haven Court Seneca, SC Discover Fair Haven Farms, an enchanting 4-acre sanctuary nestled on Lake Keowee, offering...	4 beds \| 4 baths \| N/A	$1,449,999	Airbnb cash on cash: 1.32% Traditional cash on cash: 0.84% Airbnb Rental Income: $5011 Traditional Rental Income: $3336 Airbnb ROI: 1.32% Traditional ROI: 0.84%
2119 Shea Lane Seneca, SC Welcome Home to Laid-Back Luxury Living! Discover the perfect blend of comfort and conven...	3 beds \| 3 baths \| N/A	$299,000	Airbnb cash on cash: 4.81% Traditional cash on cash: 5.07% Airbnb Rental Income: $2550 Traditional Rental Income: $2011 Airbnb ROI: 4.81% Traditional ROI: 5.07%
2123 Shea Lane Seneca, SC VERY SPACIOUS 3BR/3BA TOWNHOME WITH A MOSTLY REMODELED UPSTAIRS!!! The unit has oversized ...	3 beds \| 3 baths \| N/A	$259,000	Airbnb cash on cash: 5.78% Traditional cash on cash: 5.95% Airbnb Rental Income: $2550 Traditional Rental Income: $1977 Airbnb ROI: 5.78% Traditional ROI: 5.95%
310 Fernwood Drive Seneca, SC This charming 3-bedroom, 2-bathroom home offers the perfect combination of convenience and...	3 beds \| 2 baths \| 1,240 sq.ft.	$212,000	Airbnb cash on cash: 7.93% Traditional cash on cash: 6.29% Airbnb Rental Income: $2550 Traditional Rental Income: $1607 Airbnb ROI: 7.93% Traditional ROI: 6.29%
516 Serria Way Seneca, SC This beautiful 4 bedroom home is situated only minutes from downtown Seneca. The owners ha...	4 beds \| 3 baths \| N/A	$487,500	Airbnb cash on cash: 7.26% Traditional cash on cash: 4.39% Airbnb Rental Income: $5011 Traditional Rental Income: $2677 Airbnb ROI: 7.26% Traditional ROI: 4.39%
557 Greenbriar Drive Seneca, SC This inviting 3-bedroom, 2-bathroom home offers approx 1500 sq ft of spacious living space...	3 beds \| 2 baths \| N/A	$269,000	Airbnb cash on cash: 5.95% Traditional cash on cash: 6.92% Airbnb Rental Income: $2550 Traditional Rental Income: $2184 Airbnb ROI: 5.95% Traditional ROI: 6.92%
285 Seneca Springs Landing Road Seneca, SC Discover your dream retreat on the serene Martin Creek section of Lake Hartwell, just 15 m...	4 beds \| 4 baths \| N/A	$630,000	Airbnb cash on cash: 4.99% Traditional cash on cash: 4.9% Airbnb Rental Income: $5011 Traditional Rental Income: $3935 Airbnb ROI: 4.99% Traditional ROI: 4.9%
302 Meadowlark Lane Seneca, SC Donald Gardner beautiful custom style home on 2.96 acres and just a short drive to Lake Ke...	4 beds \| 4 baths \| N/A	$669,000	Airbnb cash on cash: 4.11% Traditional cash on cash: 2.96% Airbnb Rental Income: $5011 Traditional Rental Income: $3272 Airbnb ROI: 4.11% Traditional ROI: 2.96%
4050 Keowee School Road Seneca, SC Located on scenic Keowee School Road, this 3 bed, 1 bath home has 1,406 square feet and is...	3 beds \| 1 baths \| N/A	$264,900	Airbnb cash on cash: 5.81% Traditional cash on cash: 3.12% Airbnb Rental Income: $2550 Traditional Rental Income: $1265 Airbnb ROI: 5.81% Traditional ROI: 3.12%
3204 Tumble Stone Drive Seneca, SC REMARKS Public: Beautiful MOVE IN READY new home on a quiet cul-de-sac of Cross Creek G...	4 beds \| 3 baths \| N/A	$424,900	Airbnb cash on cash: 8.21% Traditional cash on cash: 4.28% Airbnb Rental Income: $5011 Traditional Rental Income: $2420 Airbnb ROI: 8.21% Traditional ROI: 4.28%
5007 Bridgeview Drive Seneca, SC (NO HOA) Whether you're looking for a permanent residence, a vacation retreat or a short-t...	3 beds \| 3 baths \| N/A	$1,675,000	Airbnb cash on cash: 0.06% Traditional cash on cash: 0.31% Airbnb Rental Income: $2550 Traditional Rental Income: $2317 Airbnb ROI: 0.06% Traditional ROI: 0.31%
Lot 17 Summersweet Lane Seneca, SC New Construction with customization options on this spectacular two story, four bedroom, t...	4 beds \| 3 baths \| N/A	$450,000	Airbnb cash on cash: 7.49% Traditional cash on cash: 4.1% Airbnb Rental Income: $5011 Traditional Rental Income: $2559 Airbnb ROI: 7.49% Traditional ROI: 4.1%
409 S Cove Road Seneca, SC Location, location, location! This lovely brick ranch sits on a half-acre level lot featu...	3 beds \| 1 baths \| N/A	$243,500	Airbnb cash on cash: 5.81% Traditional cash on cash: 2.67% Airbnb Rental Income: $2550 Traditional Rental Income: $1214 Airbnb ROI: 5.81% Traditional ROI: 2.67%
3100 Chatham Drive Seneca, SC LIVE WHERE YOU PLAY! This sophisticated country home encompasses the elegance of golf com...	4 beds \| 5 baths \| N/A	$950,000	Airbnb cash on cash: 2.94% Traditional cash on cash: 3.36% Airbnb Rental Income: $5011 Traditional Rental Income: $4361 Airbnb ROI: 2.94% Traditional ROI: 3.36%
1316 E South 6th Street Seneca, SC Minutes from Clemson University and Lake Hartwellâ¦ this remodeled home is the perfect pl...	3 beds \| 2 baths \| N/A	$239,999	Airbnb cash on cash: 6.81% Traditional cash on cash: 6.22% Airbnb Rental Income: $2550 Traditional Rental Income: $1803 Airbnb ROI: 6.81% Traditional ROI: 6.22%
11110 Watson Drive #D Seneca, SC Discover this charming townhome located at 11110 Watson Drive, Unit D, in Seneca, SC. Less...	3 beds \| 3 baths \| N/A	$249,000	Airbnb cash on cash: 6.01% Traditional cash on cash: 7.49% Airbnb Rental Income: $2550 Traditional Rental Income: $2284 Airbnb ROI: 6.01% Traditional ROI: 7.49%
11110 Watson Drive #C Seneca, SC BRAND NEW CONSTRUCTION! Discover this charming townhome located at 11110 Watson Drive, Uni...	3 beds \| 3 baths \| N/A	$249,000	Airbnb cash on cash: 6.01% Traditional cash on cash: 7.49% Airbnb Rental Income: $2550 Traditional Rental Income: $2284 Airbnb ROI: 6.01% Traditional ROI: 7.49%
6 Ivy Court Seneca, SC Welcome Home! This home features 3 bedrooms, 2 bathrooms, a large living and dining room c...	3 beds \| 2 baths \| N/A	$280,000	Airbnb cash on cash: 5.34% Traditional cash on cash: 4.03% Airbnb Rental Income: $2550 Traditional Rental Income: $1588 Airbnb ROI: 5.34% Traditional ROI: 4.03%
11112 Watson Drive #C Seneca, SC BRAND NEW CONSTRUCTION! Discover this charming townhome located at 11112 Watson Drive, Uni...	3 beds \| 3 baths \| N/A	$249,000	Airbnb cash on cash: 6.01% Traditional cash on cash: 7.37% Airbnb Rental Income: $2550 Traditional Rental Income: $2257 Airbnb ROI: 6.01% Traditional ROI: 7.37%
804 Longforest Drive Seneca, SC WOW!! 1864 square feet of beautifully remodeled 3 bed 2 bath home on 3 lots totaling an ac...	3 beds \| 2 baths \| N/A	$319,000	Airbnb cash on cash: 4.57% Traditional cash on cash: 3.83% Airbnb Rental Income: $2550 Traditional Rental Income: $1713 Airbnb ROI: 4.57% Traditional ROI: 3.83%
270 Meridian Way Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$389,000	Airbnb cash on cash: 2.92% Traditional cash on cash: 2.63% Airbnb Rental Income: $2550 Traditional Rental Income: $1830 Airbnb ROI: 2.92% Traditional ROI: 2.63%
260 Meridian Way Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$389,000	Airbnb cash on cash: 2.92% Traditional cash on cash: 2.63% Airbnb Rental Income: $2550 Traditional Rental Income: $1830 Airbnb ROI: 2.92% Traditional ROI: 2.63%
170 Preston Ridge Drive Seneca, SC Welcome to Preston Ridge. Oconee County's most desirable townhome development. Maintenance...	3 beds \| 2 baths \| N/A	$389,000	Airbnb cash on cash: 3.43% Traditional cash on cash: 3.14% Airbnb Rental Income: $2550 Traditional Rental Income: $1830 Airbnb ROI: 3.43% Traditional ROI: 3.14%
401 Margie Court Seneca, SC Discover your ideal home in this beautifully renovated 3-bedroom, 1.5-bathroom gem offerin...	3 beds \| 2 baths \| N/A	$209,900	Airbnb cash on cash: 7.69% Traditional cash on cash: 5.85% Airbnb Rental Income: $2550 Traditional Rental Income: $1569 Airbnb ROI: 7.69% Traditional ROI: 5.85%
106 Snug Harbor Road Seneca, SC SHORT TERM RENTALS ALLOWED, NO HOA FEES - 20 MINUTES TO CLEMSON! This fabulous 4 bedroom,...	4 beds \| 4 baths \| N/A	$599,900	Airbnb cash on cash: 5.39% Traditional cash on cash: 4.53% Airbnb Rental Income: $5011 Traditional Rental Income: $3505 Airbnb ROI: 5.39% Traditional ROI: 4.53%
1555 Fort Hill Drive Seneca, SC Welcome to your own private oasis, surrounded by beautiful mature trees and gardens to enj...	3 beds \| 3 baths \| N/A	$365,000	Airbnb cash on cash: 3.81% Traditional cash on cash: 4.17% Airbnb Rental Income: $2550 Traditional Rental Income: $2057 Airbnb ROI: 3.81% Traditional ROI: 4.17%
295 Sugarhill Road Seneca, SC Discover the charm of lakeside living at 295 Sugarhill Rd., Seneca, SC 29672. This 5-bedro...	5 beds \| 5 baths \| N/A	$1,550,000	Airbnb cash on cash: 0.42% Traditional cash on cash: 1.51% Airbnb Rental Income: $3772 Traditional Rental Income: $4519 Airbnb ROI: 0.42% Traditional ROI: 1.51%
101 Whippoorwill Drive Seneca, SC Experience breathtaking views of Lake Keowee from this fabulous 3-bedroom, 2-bath home, pe...	3 beds \| 2 baths \| N/A	$397,900	Airbnb cash on cash: 3.36% Traditional cash on cash: 3.38% Airbnb Rental Income: $2550 Traditional Rental Income: $1942 Airbnb ROI: 3.36% Traditional ROI: 3.38%
109 Granada Place Seneca, SC Welcome to this absolutely stunning home ideally located in the Tokeena Trail subdivision ...	5 beds \| 3 baths \| N/A	$454,900	Airbnb cash on cash: 5.04% Traditional cash on cash: 4.36% Airbnb Rental Income: $3772 Traditional Rental Income: $2664 Airbnb ROI: 5.04% Traditional ROI: 4.36%
331 N Summit Drive Seneca, SC Warm and welcoming custom home that has year round mountain views and seasonal Lake Keowee...	4 beds \| 4 baths \| N/A	$849,000	Airbnb cash on cash: 3.21% Traditional cash on cash: 2.36% Airbnb Rental Income: $5011 Traditional Rental Income: $3318 Airbnb ROI: 3.21% Traditional ROI: 2.36%

Real Estate investment in Seneca, SC

There are 95 properties for sale in the city of Seneca . The median list price in Seneca is $382,000 and the average price per square foot is $291. In January 2025, the average monthly cash on cash return in Seneca is 4.00%. The average monthly rental income in Seneca is $2,207.

Seneca, SC Real Estate Investing: FAQs for Buyers, Sellers and Investors

There are 95 investment properties available for sale in Seneca.

In 2025, the best neighborhood to buy investment property is Seneca.

The ROI for Short-Term is higher than the Long-Term in Seneca with average rental income of $2,550.

Your search for investment property begins and ends here

Investment Property for Sale in Seneca, SC

4014 Creekside Drive

Seneca, SC

3 beds | 2 baths | N/A

$245,000

Airbnb cash on cash: 6.72%

Traditional cash on cash: 6.22%

Airbnb Rental Income: $2550

Traditional Rental Income: $1821

Airbnb ROI: 6.72%

Traditional ROI: 6.22%

811 Harts Cove Way

Seneca, SC

3 beds | 3 baths | N/A

$250,000

Airbnb cash on cash: 5.29%

Traditional cash on cash: 6.48%

Airbnb Rental Income: $2550

Traditional Rental Income: $2217

Airbnb ROI: 5.29%

Traditional ROI: 6.48%

2600 Dog Leg Lane

Seneca, SC

3 beds | 3 baths | N/A

$719,000

Airbnb cash on cash: 1.01%

Traditional cash on cash: 1.09%

Airbnb Rental Income: $2550

Traditional Rental Income: $1990

Airbnb ROI: 1.01%

Traditional ROI: 1.09%

816 Ploma Drive

Seneca, SC

3 beds | 3 baths | N/A

$475,000

Airbnb cash on cash: 2.67%

Traditional cash on cash: 3.43%

Airbnb Rental Income: $2550

Traditional Rental Income: $2271

Airbnb ROI: 2.67%

Traditional ROI: 3.43%

413 Arbor Way

Seneca, SC

3 beds | 2 baths | N/A

$440,000

Airbnb cash on cash: 2.92%

Traditional cash on cash: 1.99%

Airbnb Rental Income: $2550

Traditional Rental Income: $1556

Airbnb ROI: 2.92%

Traditional ROI: 1.99%

636 Barnes Road

Seneca, SC

3 beds | 2 baths | N/A

$349,500

Airbnb cash on cash: 4.05%

Traditional cash on cash: 3.84%

Airbnb Rental Income: $2550

Traditional Rental Income: $1868

Airbnb ROI: 4.05%

Traditional ROI: 3.84%

1513 Harts Ridge Drive

Seneca, SC

3 beds | 3 baths | N/A

$255,000

Airbnb cash on cash: 5.23%

Traditional cash on cash: 6.61%

Airbnb Rental Income: $2550

Traditional Rental Income: $2269

Airbnb ROI: 5.23%

Traditional ROI: 6.61%

701 Bogey Boulevard

Seneca, SC

4 beds | 4 baths | N/A

$459,900

Airbnb cash on cash: 7.33%

Traditional cash on cash: 5.72%

Airbnb Rental Income: $5011

Traditional Rental Income: $3294

Airbnb ROI: 7.33%